TMZ reports Lane was found dead at a Los Angeles hotel Thursday evening.
Sources tell the gossip site paramedics were called to the Comfort Inn in Woodland Hills, CA yesterday around 5:15 PM; Lane was pronounced dead on the scene.
TMZ has been told Lane's death is being treated as an accidental overdose or a possible death from natural causes.
Investigators found a half-empty bottle of vodka and prescription medication in the hotel room.
Jani wrote the band's biggest hit "Cherry Pie" back in 1989, before eventually leaving the band to pursue a solo career.
Lane had a history of alcohol-related issues: he was ordered to serve 120 days in jail after he was arrested for DUI in 2010, his second DUI in two years.
An autopsy is scheduled for later today.
TMZ also reports the current lineup of Warrant will pay tribute to its former lead singer tonight at its concert in North Dakota.
Guitarist Erik Turner — who co-founded the band — tells the site, "We will be making a tribute before we play the song 'Heaven' tonight. We never thought that when the song 'Heaven' was written we would be playing it some day in the memory of Jani's untimely death. This is a very sad day for rock and roll. One of the great things about music is that it lives on forever."
Warrant
Warrant – Heaven (1989)